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Catalog/Bulletin 2012-2013 
    
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Catalog/Bulletin 2012-2013 [ARCHIVED CATALOG]

Courses

 

Anatomy
  

  • ANAT 5407 - Advanced Head & Neck Anatomy

    Postgraduate Head and Neck Anatomy is a clinically-oriented course which deals with human anatomical structure, embryological development, function and dysfunction of the head and neck in its relationship to clinical practice. This course is designed as an advanced course in head and neck anatomy for post-graduate students in medicine, dentistry and the School of Graduate Studies. The course will include segments on the basic gross anatomy, developmental anatomy, cell biology, neuroanatomy and neurophysiology of the head and neck. Special emphasis on functional considerations and clinical correlations will be given in the course.
  

  • ANAT 6522 - Human Anatomy

    [5 Credits]
    A lecture and laboratory course which focuses on cell, tissue, organ and body system structures, and human cadaver dissection with emphasis on structure and function of neuromuscular and skeletal systems.
  

  • ANAT 6533 - Neuroanatomy

    [4 Credits]
    A study of anatomy of the central and peripheral nervous systems with emphasis on structures commonly involved in pathological conditions that impact function.

Anesthesiology
  

  • ANES 419 - Anesthesiology Acting Internship

    [152 Hours]
    This four week rotation provides senior students with the opportunity to begin functioning as interns with supervision from faculty and upper level residents. Particular emphasis is given to improving skills of clinical judgment and decision making. Students are encouraged to take increasing amounts of patient care responsibility while under close supervision. In addition to improving their patient care skills, students will also enhance their communication skills and develop skills in systems based practice through their involvement with the health care team. Students will continue to develop their medical knowledge and skills of practice based learning through reading, didactic lectures, and conferences.
  

  • ANES 419 - Anesthesiology Secondary Acting Internship

    [152 Hours]
    This four week rotation provides senior medical students with the opportunity to be actively involved in the specialty of anesthesiology. Working in areas such as the preoperative clinics, operating rooms, post anesthetic care units and chronic pain clinics, will give the student exposure to the various roles of patient care that an Anesthesiologist provides. Objectives of this course will be; Assess and evaluate preoperative risk factors for anesthesia and surgery, basic airway management assessment, describe the principles of applied physiology and pharmacology in anesthesia, basic management of fluids and electrolytes in patients undergoing anesthesia. Students will be expected to attend lectures, conferences, read and review current literature. Completion of a written case report or review article will be expected at the end of the rotation.
  

  • ANES 420 - Anesthesiology Clinical

    [152 Hours]
    This four week rotation provides senior medical students the opportunity to be actively involved in the operating room environment. Working in this unique area will give the student exposure to the specialty of anesthesiology. Objectives of this course will be; Assess and evaluate preoperative risk factors for anesthesia and surgery, Basic Airway Management assessment, describe the principles of applied physiology and pharmacology in anesthesia, basic management of fluids and electrolytes in patients undergoing anesthesia. Students will be expected to attend lectures, conferences, read and review current literature. Completion of a verbal case report or literature review will be expected at the end of the rotation.
  

  • ANES 498 - Anesthesiology Research

    [152 Hours]
    This four week rotation provides senior medical students the opportunity to actively be involved in various research aspects of this specialty with the Chairman of the Department. The student will be exposed to the many facets of publication, introductions to writing grant proposals, and gaining approval from various institutional review boards. Lab research and /or clinical research projects may be conducted under direction from the Chairman. Upon completion of this rotation, the student will be expected to write a review article for publication.

Behavioral and Community Health Sciences
  

  • BCHS 6212 - Behavioral Science Theories in Public Health Practice

    [3 Credits]
    This course is designed to expose students to the origin and use of behavioral and psychosocial theories in public health research and practice. Specifically, this course will explore how theoretical concepts, constructs, frameworks and models are utilized in developing, implementing and evaluating public health interventions.
  

  • BCHS 6213 - Community Analysis, Ecology, and Health Disparities

    [3 Credits]
    The purpose of this course is to identify and understand how multiple social determinants of health contribute to health disparities at the community level. This course examines the use of quantitative and qualitative research methods to track health disparities and monitor progress of public health interventions designed to reduce or eliminate health disparities at the community level. Prerequisite: First year Core Courses.
  

  • BCHS 6214 - Health Communication

    [3 Credits]
    Providing a foundation in the science, theory, and practice of effective health communication, this course also prepares the student to develop, deliver, and evaluate health communication campaigns and disseminate information to a wide variety of potential audiences. Prerequisite: BCHS 6212 
  

  • BCHS 6215 - Monitoring and Evaluation

    [3 Credits]
    The purpose of this course is to introduce the student to the concepts of monitoring and evaluation of community, health promotion, and other public health programs. This course presents models, techniques, and practices of designing and implementing program evaluation plans. Prerequisite: EPID 6210 
  

  • BCHS 6216 - Health Program Development and Planning

    [3 Credits]
    This course provides the student with a review of the basic principles and methods for planning, executing, monitoring, and evaluating health promotion and health education intervention programs. Prerequisite: BCHS 6212 
  

  • BCHS 6217 - Community Based Participatory Programming

    [3 Credits]
    This course introduces the student to the concepts of community-based participatory research and interventional programming in public health. This course presents concepts, models, techniques, and practices useful in developing a collaborative program. Prerequisite: EPID 6210  and BCHS 6212 
  

  • BCHS 6218 - Principles of Rural Health

    [3 Credits]
    The purpose of this course is to provide the student with an overview of healthcare and access issues involved in rural areas of the US.
  

  • BCHS 6219 - Behavior Theory Applications

    [3 Credits]
    The purpose of this course is to expand the student’s knowledge of the analytic and research methods applied in the behavioral and health sciences. This course presents an overview of how these are used to inform the design, implementation, and evaluation of research and interventions within the context of established behavioral theories and models. Prerequisite: BCHS 6212 
  

  • BCHS 6220 - Issues in Maternal, Child and Adolescent Health

    [3 Credits]
    This course examines the history, organization, and financing of Maternal and Child Health (MCH) services in the U.S and to provide an overview of the health, social, economic, and policy issues currently affecting reproductive age women, infants, children and adolescents. This course presents practices of assessing MCH related data and retrieving evidence-based interventions and translating data/evidence into policy recommendations. Prerequisite: BCHS 6212 
  

  • BCHS 6221 - Survey Design

    [3 Credits]
    The purpose of this course is to gain the knowledge necessary to develop and execute a survey and analyze the collected data. Students will gain knowledge essential to design, create, and conduct a survey project. Utilizing knowledge gained from prerequisites, students will be able to analyze the survey data and determine its quality. Prerequisite: BIOS 6100 
  

  • BCHS 6222 - Chronic Disease Prevention and Management

    [3 Credits]
    This course introduces the public health student to current issues in chronic disease management, including challenges in disease prevention and management, the population-based perspective of chronic disease, integrating clinical preventive services into chronic care, and issues of public policy that impact the burden of chronic illness. Prerequisite: BCHS 6212 
  

  • BCHS 6223 - Public Health Implications of an Aging Society

    [3 Credits]
    This course prepares the public health student to address health promotion, chronic disease self-management and other behavioral and quality of life issues of health care for an aging society. Prerequisite: EPID 6210  and BCHS 6212 
  

  • BCHS 6224 - Health Related Physical Activity

    [3 Credits]
    This course introduces the student to the role physical activity and nutrition contribute to creating and maintaining optimum health.
  

  • BCHS 6225 - Infectious Disease: A Public Health Response

    [3 Credits]
    This course provides the student with an overview of the impact of infectious diseases on the populations’ health. This course will focus on the public health burden of infectious diseases and public health measures to prevent and control infectious diseases.
  

  • BCHS 6227 - Research Methods in the Health Sciences

    [3 Credits]
    The purpose of this course is to provide students with a practical introduction to conducting research and preparing reports using quantitative methods in a structured environment. This course presents an overview of how theory is used to inform the design, implementation, and evaluation of research and interventions. Students will conduct guided research projects using secondary data analysis. Prerequisite: EPID 6210  and BIOS 6100
  

  • BCHS 6400 - Independent Study

    [1-3 Credits]
    This course provides the student an opportunity to study a topic in depth while under the guidance of a faculty member. The focus of the course will be a specific aspect of a public health discipline which is not the primary focus of exiting public health courses. The course will involve directed readings and may require completion of a paper or study project that provides evidence of comprehension and professional proficiency in the area studied. Independent Study may only be taken for a maximum of 3 credit hours toward the MPH Degree.
  
  

  • BCHS 6700 - Behavioral and Community Health Seminar

    [1 Credit]
    (P/F) This seminar will address a variety of topics related to behavioral and community health. Each seminar will be taught by BCHS faculty and/or guest speakers.
  

  • BCHS 7201 - Ecological Approaches to Community Health Sciences

    [3 Credits]
    This course introduces students to the concept that health-related outcomes involve the interaction of the individual with the environment at multiple levels. The ecological approach addresses how both individual-level risk factors, as well as beliefs, attitudes, and perceptions, may be moderated and/or mediated by environmental and social factors, such as norms, social networks, and cultural values, to affect health outcomes. Mirroring the complexity of contemporary public health problems, the major variables in social ecological models are multi-level and their influence is bi-directional. Students will learn to use this approach to address several major public health issues, including health disparity, smoking, obesity, and addiction. Class activities will include lecture, group projects, films, and discussion.
  

  • BCHS 7202 - Health Behavior Change

    [3 Credits]
    This is an advanced course on theoretical and practical aspects of health behavior change. The course is designed to provide an understanding of theoretical issues and current methodologies influencing health behavior change. Several models of health behavior changes will be studied in detail. The strengths and shortcomings of these models for the development and evaluation of interventions at individual, community and system levels will be critically assessed. Students will be expected to translate their knowledge into practical interventions for health behavior change.
  

  • BCHS 7203 - Advanced Research Methods in Community Health Sciences

    [3 Credits]
    Designed for doctoral students, the purpose of this course is to provide students with a practical introduction to conducting research and preparing reports using quantitative methods in a structured environment. This course presents an overview of how theory is used to inform the design, implementation, and evaluation of research and interventions. Students will conduct guided research projects using secondary data analysis.
  

  • BCHS 7207 - Advanced Community Analysis, Ecology and Health Disparities

    [3 Credits]
    Designed for doctoral degree students, this course is to identify how multiple social determinants of health contribute to health at the community level. This course examines the use of quantitative and qualitative research methods to evaluate health behaviors and monitor progress of public health interventions designed to promote health behaviors or eliminate health disparities at the community level.
  

  • BCHS 7217 - Advanced Community Based Participatory Programming

    [3 Credits]
    Designed for doctoral degree students, this course introduces the student to the concepts of community-based participatory research and interventional programming in public health. This course presents concepts, models, techniques, and practices useful in developing a collaborative program.
  

  • BCHS 7218 - Advanced Principles of Rural Health

    [3 Credits]
    Designed for doctoral degree students, this course provides the student with an overview of healthcare and access issues involved in rural areas of the US.
  

  • BCHS 7220 - Advanced Issues in Maternal, Child and Adolescent Health

    [3 Credits]
    Designed for doctoral degree students, this course examines the history, organization, and financing of Maternal and Child Health (MCH) services in the U.S and provides an overview of the health, social, economic, and policy issues currently affecting reproductive age women, infants, children and adolescents. This course presents practices of assessing MCH related data and retrieving evidence-based interventions and translating data/evidence into policy recommendations.
  

  • BCHS 7221 - Advanced Survey Design

    [3 Credits]
    Designed for doctoral degree students, this course provides the knowledge necessary to develop and execute a survey and analyze the collected data. Students will gain knowledge essential to design, create, and conduct a survey project. Utilizing knowledge gained from prerequisites, students will be able to analyze the survey data and determine its quality.
  

  • BCHS 7222 - Advanced Chronic Disease Prevention and Management

    [3 Credits]
    Designed for doctoral degree students, this course introduces the public health student to current issues in chronic disease management, including challenges in disease prevention and management, the population-based perspective of chronic disease, integrating clinical preventive services into chronic care, and issues of public policy that impact the burden of chronic illness.
  

  • BCHS 7223 - Advanced Public Health Implications of an Aging Society

    [3 Credits]
    Designed for doctoral degree students, this course prepares the public health student to address health promotion, chronic disease self-management and other behavioral and quality of life issues of health care for an aging society.
  

  • BCHS 7224 - Advanced Health Related Physical Activity

    [3 Credits]
    Designed for doctoral degree students, this course introduces the student to the concepts of community-based participatory research and interventional programming in public health. This course presents concepts, models, techniques, and practices useful in developing a collaborative program.
  

  • BCHS 7225 - Advanced Infectious Disease: A Public Health Response

    [3 Credits]
    Designed for doctoral degree students, this course provides the student with an overview of the impact of infectious diseases on the populations’ health. This course will focus on the public health burden of infectious diseases and public health measures to prevent and control infectious diseases.
  

  • BCHS 7350 - Translational Research

    [3 Credits]
    This course will focus on multidisciplinary research skills needed to carry out bench to bedside to community health and population translational research. The primary objective of the program is to train individuals to interpret basic and clinical science research and apply this knowledge to the development of community health and population research projects. Students will gain expertise in research study design, statistical methodology, translational research technologies, grant and scientific writing skills, evaluation and dissemination strategies.
  

  • BCHS 7351 - Race/Ethnicity, Gender and Health Disparities

    [3 Credits]
    This course will explore the interconnection between race/ethnicity, gender and health by examining theoretical and research paradigms from sociology, anthropology, policy studies and public health. The course will explore how race/ethnicity and gender are shaped by political, social, economic, geographical and organizational factors and contribute to variations in health outcomes according to social class, geographical location, and social economic position. Class activities include: 1) class discussion with regard to how race/ethnicity and gender translate into unequal distribution of power that simultaneously operate at both the macro (societal) and micro (individual) levels of society; 2) data collection approaches and analytical methods to identify and understand links between race/ethnicity, gender and health; and 3) discussions concerning the role of public health in identifying ways to utilize emerging research regarding race/ethnicity, gender and health to advance public health research and practice.
  

  • BCHS 7352 - Mental Health Promotion in Community Health Science

    [3 Credits]
    This course exposes students to the emerging field of mental health promotion; its history, principles, theories; and its differences and linkages to mental illness prevention. The course objectives are to impart knowledge of the basic principles of mental health promotion; teach the many factors causal to mental illness and the maintenance of mental health; and afford students an understanding of the complexity and multiplicity of disciplines involved in the practice of mental health promotion. In this course, students will review trends (vital statistics and epidemiology) in mental health among different populations as well as the risk and protective factors associated with mental health. Students will explore the sociocultural definitions and impact of mental health, mental illness, and stigma. The course describes a conceptual paradigm for mental health promotion from both policy and practice frameworks, including assessment, consultation, education, and training.
  

  • BCHS 7410 - CHS Teaching Practicum

    [2 Credits]
    (P/F) This course will provide doctoral students in Community Health Sciences with supervised teaching experience to develop their pedagogical skills. This experience will come primarily from serving in the role of teaching assistants for Behavioral and Community Health Sciences courses. Developmental workshops and materials offered by the LSU Health Sciences Center’s Academy for the Advancement of Education Scholarship will be incorporated as part of the training experience.
  

  • BCHS 7700 - Community Health Sciences Seminar I

    [1 Credit]
    (P/F) This course provides students with a broad overview of issues in behavioral and community health sciences. Each session will address a different topic related to research and practice and will be taught by both CHS faculty and visiting professors.
  

  • BCHS 7701 - Community Health Sciences Seminar II

    [1 Credit]
    (P/F) This course provides students with a broad overview of issues in behavioral and community health sciences. Each session will address a different topic related to research and practice and will be taught by both CHS faculty and visiting professors.
  

  • BCHS 7702 - Community Health Sciences Seminar III

    [1 Credit]
    (P/F) This course provides students with a broad overview of issues in behavioral and community health sciences. Each session will address a different topic related to research and practice and will be taught by both BCHS faculty and visiting professors.
  

  • BCHS 7900 - Dissertation Research

    [1-11 Credits]
    (P/F) For doctoral candidates conducting research for their dissertation. Registration by permission of the program. Amount of credit must be stated at the time of registration.

Biochemistry and Molecular Biology
  

  • BIOCH 100 - Biochemistry

    [80 Hours]
    This course provides the foundation for the study of normal and diseased states at the molecular level. The following topics are included in the course of study: macromolecular structure and function; enzymology and enzyme kinetics; intermediary metabolism of carbohydrates, lipids, and amino acids; the metabolic basis of disease; nutrition, vitamins, and obesity; endocrine biochemistry; molecular biology (including DNA, RNA, protein synthesis, molecular diagnostics, and the molecular basis of cancer); and the foundations of medical genetics (including chromosome structure and function, chromosomal disorders, inheritance patterns, the genetic basis of metabolic disorders and cancer, and population genetics). Particular emphasis is placed upon the medical relevance of biochemical concepts, and the biochemical defects that result in human disease. Modern, up-to-date developments are used to build upon classical concepts in order to provide students with the background necessary to be excellent physicians who are well-equipped to diagnose and treat patients. The course consists of lectures and review sessions.
  

  • BIOCH 207 - Introduction to Special Methods of Research

    [1-9 Credits]
    Theoretical discussions and laboratory work during the first year of laboratory rotations, as well as research related work for graduate students prior to passing the Qualifying Examination. Prerequisite: Consent of instructor.
  

  • BIOCH 208 - Cell Culture Techniques

    [1 Credit]
    A course in contemporary cell culture techniques. Prerequisite: Consent of instructor.
  

  • BIOCH 221 - Protein Chemistry

    [2 Credits]
    Didactic and discussion sessions covering advanced aspects of protein structure-function; thermodynamics of protein folding; protein evolution; bioinformatics analysis of protein superfamilies; techniques of protein expression; purification and characterization of natural and recombinant proteins. Prerequisite: INTER 111.
  

  • BIOCH 223 - Physical Biochemistry

    [3 Credits]
    Didactic and discussion sessions covering the thermodynamic and biophysical properties of biochemically relevant macromolecules and their intramolecular interactions. Prerequisite: INTER 111  and one semester of calculus. Two semesters of physical chemistry is highly recommended, otherwise, permission of the course director is required.
  

  • BIOCH 260 - Cancer Molecular Genetics and Applications

    [3 Credits]
    This upper level course examines the types of genetic alterations that contribute to cancer development and discusses some of the underlying biochemical principals that result from these genetic alterations. By the end of the course, students should understand that various genotoxic stresses and subsequent genetic alterations can induce cancer development as well as promote in tumor progression. Further, students should be familiar with different approaches to identify candidate genes for cancer development and tumor progression. The class will involve two, two-hour lectures per week. It is offered jointly with the Dept of Genetics as GENET 245 . Prerequisite: INTER 111  and INTER 121 , INTER 122 , INTER 123  and INTER 124 .
  

  • BIOCH 280 - Advanced Topics in Biochemistry

    [1-4 Credits]
    timeliness and student and faculty interest. Biochemistry of the cell cycle, comparative biochemistry, enzymology, intermediary metabolism, vitamins and nutrition, mass spectrometry, and bioenergetics are representative topics. A given topic will recur on a cycle of two to three years. The student’s transcript will indicate, in addition to the course title, the particular topic covered during the given semester. This procedure will serve to clarify the repeat appearance of Biochemistry 280 on the student’s transcript.
  

  • BIOCH 298 - Seminar

    [1 Credit]
    (S/U) Reports on research progress and on current literature. Six credits of seminar (either BIOCH 298 or BIOCH 299 ) are required for departmental program of study, but note that the School of Graduate Studies permits only four credits of seminar to be applied toward graduation.
  

  • BIOCH 299 - Professional Skills for Graduate Students

    [1 Credit]
    (S/U) Didactic and discussion sessions covering different ‘soft’ skills required for success in academic and industry career tracks. Topics can range from manuscript writing and submission procedures, grant writing, interview skills, methods of negotiation, pedagogical metrics, and resume development. The Department requires that all students enroll for the course, unless they are enrolled in BIOCH 999  (Exam Only). Six credits of seminar (either BIOCH 298  or BIOCH 299) are required for departmental program of study, but note that the School of Graduate Studies permits only four credits of seminar to be applied toward graduation.
  

  • BIOCH 300 - Thesis Research

    [1-6 Credits]
    (S/U) Research for PhD degree students after successful completion of the Qualifying Exam and prior to passing the Preliminary Exam. Prerequisite: Consent of instructor.
  

  • BIOCH 400 - Dissertation Research

    [1-9 Credits]
    (S/U) Full-time research efforts toward the thesis for PhD degree students after successful completion of the Preliminary Exam. Prerequisite: Consent of instructor.
  

  • BIOCH 999 - Exam Only

    [0 Credits]
    (P/F) Students may register for “Exam Only” when they have completed their Preliminary Exam and expect to complete PhD requirements and graduate within 3 semesters. Students are allowed to register for “Exam Only” for a maximum of 3 semesters.

Biostatistics
  

  • BIOS 3115 - Basic Statistics

    [3 Credits]
    A study of scientific methodology and the use of statistics in design and analysis of studies in the health sciences. Consideration is given to fundamentals of sample selection, measures of central tendency, measures of variation, correlation coefficients, and tests of hypotheses. 3 hours lecture. Prerequisite: college algebra
  

  • BIOS 6100 - Biostatistical Methods I

    [4 Credits]
    This course is a general introduction to descriptive and inferential statistics: The role of biostatistics in the health sciences, techniques and principles for summarizing data, estimation, hypothesis testing and decision-making. Examples and problems from the health sciences are used. The course includes laboratory exercises.
  

  • BIOS 6100 - Biostatistical Methods I

    [4 Credits]
    Three hours of lecture and two hours of lab per week. General introduction to descriptive and inferential statistics: techniques and principles for summarizing data, estimation, hypothesis testing and decision-making. Students are instructed on the proper use of statistical software to manage, manipulate, and analyze data and to prepare summary reports and graphical displays. Examples and problems from the health sciences are used throughout. Laboratory sessions will be held in the SPH computing lab and are designed to closely follow the lecture material. (Non-biostatistics majors only)
  

  • BIOS 6102 - Biostatistical Methods II

    [4 Credits]
    This course is a continuation of BIOS 6100. Additional biostatistics techniques in health sciences: Hypothesis testing via the general linear model, including analysis of variance and linear regression, methods of correlation analysis, and multiple regression techniques. Examples and problems from the health sciences are used. Includes laboratory exercises. Prerequisite: BIOS 6100
  

  • BIOS 6200 - Principles of Applied Statistics

    [4 Credits]
    Three hours lecture and two hours of lab per week. Broad coverage of methods of applied statistics, designed for students who want to take advantage of their good math backgrounds for better understanding. Data description; elementary probability, random variables, distributions; principles of statistical inference; methods for on-two-, and multi-sample settings, including ANOVA and multiple regression; methods for categorical responses. Use of SAS and other software for analysis, simulations, graphics, and report writing. Some cases will use large national databases, such as NHANES and CPS. Laboratory sessions will be held in the SPH computing lab and are designed to closely follow the lecture material. Prerequisite: multi-variable calculus and linear algebra.
  

  • BIOS 6202 - Applied Linear Models

    [3 Credits]
    Three hours of lecture per week. This is a practical course on the use of general linear models. Topics include a review of relevant matrix algebra; general linear models including multiple regression, analysis of variance, analysis of covariance, multivariate response, and logistic regression models; methods for estimation, hypothesis testing and diagnostics; model specification for designed experiments and for observational studies; applications are in the health sciences. Prerequisite: BIOS 6100 or BIOS 6200 .
  

  • BIOS 6204 - Statistical Theory I

    [3 Credits]
    Three hours of lecture per week. Elementary concepts of probability; conditional probability, Bayes’ theorem; random variables and probability distributions, transformations of random variables; moments and moment generating functions; discrete and continuous random variables, common families of distributions; essential inequalities and identities; multivariate distributions, joint, conditional and marginal distributions; covariance and correlation, conditional expectation; basic concepts of random samples; convergence concepts, convergence in probability and in distribution, the law of large numbers, and the central limit theorem. Prerequisite: multivariate calculus and linear algebra.
  

  • BIOS 6206 - Statistical Theory II

    [3 Credits]
    Three hours of lecture per week. Principles of data reduction, sufficiency and completeness, minimal sufficient statistics; the likelihood principle; point estimation, method of moments, maximum likelihood estimation; methods of evaluating estimators, unbiased estimation, Fisher information, hypotheses testing, likelihood ratio tests, methods of evaluating tests, methods of evaluating interval estimators Prerequisite: BIOS 6204 
  

  • BIOS 6210 - Categorical Data Analysis

    [3 Credits]
    Three hours of lecture per week. Model formulation, parameter estimation, and hypothesis testing for categorical data from different types of experimental and survey research situations: Characterization of interaction in multidimensional contingency tables, stepwise regression procedures for proportions, and exact inference. Prerequisite: BIOS 6102 or BIOS 6202 .
  

  • BIOS 6212 - Survival Analysis

    [3 Credits]
    Three hours of lecture per week. This course provides students with statistical methodology for the analysis of time-to-event data and trains students in the appropriate analysis of survival data, by both parametric and nonparametric methods. Emphasis will be placed on methods and models most useful in clinical research with attention to proper interpretation of statistical packages output. Prerequisite: BIOS 6102 or BIOS 6202 .
  

  • BIOS 6221 - Biostatistical Methods I

    [4 Credits]
    Three hours of lecture and two hours of lab per week. General introduction to descriptive and inferential statistics: techniques and principles for summarizing data, estimation, hypothesis testing, and decision-making. Students are instructed on the proper use of statistical software to manage, manipulate, and analyze data and to prepare summary reports and graphical displays. Examples and problems from the health sciences are used throughout. Laboratory sessions will be held in the SoPH computing lab and are designed to closely follow lecture material. (Non-biostatistics majors only.)
  

  • BIOS 6300 - Statistical Computing

    [3 Credits]
    Three hours of lecture per week, summer semester. An introductory programming course oriented toward statistical applications using SAS (including IML) and the R programming languages. Topics include data types, assignment statements, operators, sequential control, conditional control, iteration, subprograms, arrays, character manipulation, manipulating and processing SAS output from SAS procedures, Gibbs sampler, and Markov Chain Monte-Carlo methods. Prerequisite: BIOS 6202  or permission of the instructor.
  

  • BIOS 6302 - Longitudinal Data Analysis

    [3 Credits]
    Three hours of lecture per week. This course will emphasize analysis and interpretation of data obtained from subjects measured repeatedly over time. Coverage will begin with traditional approaches to analysis of longitudinal data such as multivariate repeated measures and the univariate analysis of repeated measures as a split-plot model and will quickly lead into models for mean response such as the analysis of response profiles and parametric curve fitting including linear splines. Models for the covariance matrix will be then be considered. Linear mixed models and generalized estimation equations will be covered in detail. Other topics will be covered as time allows. Examples from the health and biomedical sciences will be presented to motivate the material. Prerequisite: BIOS 6102 or BIOS BIOS 6202 .
  

  • BIOS 6304 - Design and Analysis of Experiments

    [3 Credits]
    Three hours of lecture per week. Principles of experimentation. Completely randomized designs, randomized complete block designs, factorial designs, Latin squares, crossover designs, blocking, response surface designs. Applications in the health sciences. Prerequisite: BIOS 6100 or BIOS 6200 , or permission of the instructor.
  

  • BIOS 6308 - Multivariate Methods

    [3 Credits]
    Three hours of lecture per week. Review of matrix algebra, multivariate normal distribution, multivariate general linear model, principal components, factor analysis, cluster analysis, discriminate analysis. Applications to the health sciences. Prerequisite: BIOS 6202 , BIOS 6206 .
  

  • BIOS 6310 - Applied Bayesian Methods

    [3 Credits]
    Three hours of lecture per week. Introduction to Bayesian approach to statistical inference. Application orientated, but such theory as is necessary for a proper understanding of the Bayesian methodology will be covered. Topics covered include Bayesian Inference – prior determination, point and interval estimation, hypothesis testing, prediction, model assessment and model choice; Bayesian Computation – Markov Chain Monte Carlo (MCMC) methods. Gibbs Sampling and extensions; and Bayesian applications on real data sets from the biological or medical fields. Prerequisite: BIOS 6102 (or BIOS 6202 ), BIOS 6206 , BIOS 6300 , or permission of the instructor.
  

  • BIOS 6312 - Sampling Methods

    [3 Credits]
    Three hours of lecture per week. Methods for conducting sample surveys in the health sciences: Biases and non-sampling errors, probability and non-probability samples, simple random sampling, stratification, varying probabilities of selection, multi-stage sampling, systematic sampling, cluster sampling, double sampling, and ratio estimation. Prerequisite: Permission of the instructor
  

  • BIOS 6314 - Clinical Trials Methodology

    [3 Credits]
    Three hours of lecture per week. Introduction to the conduct of clinical trials and clinical trials methodology. Topics covered include selection of primary and secondary research questions and hypotheses, use of surrogate variables, defining study population, generalizability of results, basic study design, randomization process, blinding, sample size estimation, using baseline assessments, recruitment of study participants, data collection and quality control, assessing and reporting adverse events, assessing quality of life, participant adherence, survival analysis techniques and issues, monitoring response variables, data analysis issues, study closeout, and reporting and interpreting results. Prerequisite: BIOS 6102 or BIOS 6202 .
  

  • BIOS 6316 - Stochastic Processes

    [3 Credits]
    Three hours of lecture per week. Markov chains; birth-death processes; random walks; renewal theory; Poisson processes; Brownian motion; branching processes; martingales; with applications. Prerequisite: BIOS 6206 .
  

  • BIOS 6400 - Independent Study

    [1-3 Credits]
    This course provides the student an opportunity to study a topic in depth while under the guidance of a faculty member. The focus of the course will be a specific area within biostatistics which is not the primary focus of an existing biostatistics course. The course will involve directed readings and may require completion of a paper or study project that provides evidence of comprehension and proficiency in the area studied. Independent Study may only be taken for a maximum of 3 credit hours toward the MPH Degree.
  

  • BIOS 6450 - Design and Analysis of Expression Studies

    [3 Credits]
    Three hours of lecture per week. Introduction to DNA, RNA, protein and gene expression; statistical methods; microarray technology; data visualization and quality control; variability in microarray data; specific and non-specific hybridization—background correction; normalization and transformation; gene expression summarization; missing value problems; detection of differentially expressed genes; design of microarray experiments. Prerequisite: BIOS 6202 .
  

  • BIOS 6500 - Special Topics in Biostatistics

    [1-4 Credits]
    This course is designed depending upon student’s interest and faculty availability, to cover advanced topics such as time series analysis, machine learning, bioinformatics, robust statistics, etc. The hours and credits will be arranged depending on the particular topic.
  
  

  • BIOS 6610 - Biostatistical Consulting

    [2 Credits]
    A practical course designed to expose students to real-life consulting situations and the statistical problems that arise in the health sciences. The student will work on a consulting project under the supervision of a faculty member and will present a progress report each week. Prerequisite: BIOS 6202 .
  

  • BIOS 6700 - Research Seminar in Biostatistics

    [2 Credit]
    Reports on research progress in current literature. Students attend colloquium and give an oral presentation in their second year.
  

  • BIOS 6900 - Thesis Research

    [1-6 Credits]
    (P/F) Registration by permission of the program. Amount of credit must be stated at time of registration.
  

  • BIOS 7200 - Theory of Linear Models

    [3 Credits]
    Three hours of lecture per week. This course presents the essentials of statistical inference theory for general linear models. Topics include a review of relevant matrix algebra; distributions of quadratic forms; theoretical aspects of estimation, hypothesis testing and diagnostics. Prerequisite: BIOS 6202 , BIOS 6206 , or permission of the instructor.
  

  • BIOS 7202 - Generalized Linear Models

    [3 Credits]
    Three hours of lecture per week. Study of parametric models in the exponential family of distributions including the normal, binomial, Poisson, and gamma. Parameter estimation with iterative re-weighted least squares and quasi-likelihood methods. Modeling of correlated data or data with non-constant variance via mixed models (e.g., GLIMMIX). In-depth coverage of generalized estimating equations (GEE1 and GEE2) and quadratic estimating equations (QEE). Applications with be presented from a variety of settings such as the basic sciences, medicine, dental, and public health. Prerequisite: BIOS 6202 , BIOS 6206 , or permission of the instructor.
  

  • BIOS 7204 - Advanced Statistical Theory I

    [3 Credits]
    Three hours of lecture per week. A mathematical study of the classical theory of statistical inference. Moment generating functions and characteristic functions, distributions of order statistics, exponential family of distributions, models of convergence, the Cramer-Rao inequality, efficiency, best unbiased estimation, completeness, minimal sufficiency, maximum likelihood estimators; monotone likelihood ratio, unbiased and invariant hypothesis tests, generalized likelihood ratio tests, Bayes’ and minimax procedures. Prerequisite: BIOS 6206 .
  

  • BIOS 7205 - Advanced Statistical Theory II

    [3 Credits]
    Three hours of lecture per week. A mathematically rigorous survey of selected topics in the theory of statistical inference such as: Bayesian inference, decision theory, information theory, large sample theory, multivariate distributions, nonparametric inference, sequential analysis, stochastic processes, time series, components of variance. Prerequisite: BIOS 7204 .
  

  • BIOS 7302 - Mixed Models

    [3 Credits]
    Three hours of lecture per week. Rigorous course on the theory of mixed models. Essentials of relevant matrix algebra; distribution of quadratic forms; models with variance-covariance components; one-way, two-way random and mixed models with fixed effects; methods of estimation of variance components; ML, REML, ANOVA; estimation of fixed effects; testing hypotheses about fixed effects; repeated measures design methods; choices of covariance structures; generalized linear mixed models. Prerequisite: BIOS 7200 .
  

  • BIOS 7410 - Teaching Practicum in Biostatistics

    [1-3 Credits]
    Advanced PhD students in Biostatistics working under the supervision of a faculty member will have the opportunity to gain valuable in-class teaching experience. Students will be intensively involved in all aspects of course teaching and administration. Working closely with a faculty member, the student will prepare a syllabus, lectures, handouts, quizzes, and exams. The student will also be responsible for all grading of homework, quizzes and exams. The faculty member will evaluate each of the lectures, providing direction, advice and feedback to the student. A written evaluation detailing the student’s performance will be provided as feedback to the student and will be the basis for the (Pass/Fail) grade. Each PhD student in Biostatistics is required to successfully complete at least 3 hours of supervised teaching before graduation. Prerequisite: Successful completion of the qualifying exam at the PhD level.
  

  • BIOS 7900 - Dissertation Research

    [15 Credits]
    (P/F) Registration by permission of the program. Amount of credit must be stated at time of registration.

Cardiopulmonary Science
  

  • CPSC 3100 - Introduction to the Clinical Cardiopulmonary Sciences

    [1 Credit]
    Lecture course designed to introduce students to various aspects of respiratory therapy and cardiovascular technology. Course content includes a review of medical terminology along with discussions related to ethical and legal issues encountered in the allied health sciences.
  

  • CPSC 3130 - Cardiopulmonary Human Gross Anatomy

    [5 Credits]
    Lectures on cell, tissue, organ, and body systems, structures, and dissection of human cadaver with emphasis on structure and function of the cardiovascular and respiratory systems.
  

  • CPSC 3200 - Respiratory Therapy Fundamentals

    [3 Credits]
    Lecture/laboratory course covering general principles of respiratory therapy modalities and techniques.
  

  • CPSC 3210 - General Pharmacology

    [3 Credits]
    A study of the medications and drugs that affect cardiopulmonary function and the therapeutic agents used by pulmonary and cardiovascular health care professionals. Review of pathogenic and nonpathogenic microorganisms found in the respiratory system and which may contaminate respiratory therapy and diagnostic equipment.
  

  • CPSC 3220 - Cardiopulmonary Physiology

    [3 Credits]
    This course presents a detailed analysis of cardiopulmonary physiology. The emphasis is placed on structure and function and whenever possible clinical applications will be introduced to enhance an understanding of the normal cardiopulmonary system.
  

  • CPSC 3270 - Patient Assessment

    [3 Credits]
    A lecture/laboratory course designed to teach basic patient assessment skills in a disease state management model. Students will refine interpersonal communication skills and develop a comprehensive, well organized approach for assessing patients in any clinical setting.
  

  • CPSC 3280 - Cardiopulmonary Pathophysiology

    [3 Credits]
    This course is designed to introduce the student to common pulmonary and cardiovascular disease processes and how these diseases affect respiratory and cardiovascular function. Emphasis is placed on pathogenesis, history and physical findings, diagnostic findings, and clinical management of each disease entity. Students will be able to differentially diagnose diseases covered in lecture.
  

  • CPSC 3282 - Clinical Echocardiography I

    [4 Credits]
    A lecture/laboratory course designed to introduce the student to two-dimensional and Doppler echocardiography, and their application in the diagnosis of systolic and diastolic cardiac dysfunction and valvular heart disease.
  

  • CPSC 3285 - Respiratory Clinics I

    [3 Credits]
    This course is the first of four clinical courses during which students develop the clinical skills necessary to become a competent respiratory care professional. In this course, students will gain competence in the respiratory care of adult patients receiving non-intensive care. Emphasis is placed on routine patient care, including such modalities as oxygen therapy, use of aerosol humidity devices, aerosol delivery of medication, airway clearance techniques, and hyperinflation therapy.
  

  • CPSC 3290 - Principles of Cardiac Electrophysiology

    [2 Credits]
    A lecture and laboratory course covering the fundamentals of 12-lead electrocardiography, Holter monitor recordings, and stress testing protocols. Each student should be able to perform basic interpretation of these tests, and understand the electrophysiologic basis for these findings.
 

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