Aug 08, 2022  
Catalog/Bulletin 2014-2015 
Catalog/Bulletin 2014-2015 [ARCHIVED CATALOG]


[3 Credits]
Three hours of lecture per week. This course covers basic knowledge in virology and vector development for rational design and development of state-of-the-art gene and macromolecule delivery systems. Advanced technologies in evaluating and assessing gene and macromolecule transfer efficacy at the cellular and molecular level will be introduced. A general overview on the most recent advances in improving these delivery vehicles and clinical applications in the treatment of various inherited and acquired diseases will be provided. Towards the end of this course, issues related to ethical and legal concerns and regulatory approval processes through the federal government leading to human trials will be provided. Upon completion of this course, students should have a general concept of advantages and limitations of each of the gene/macromolecule transfer systems and understanding of the process from “bench” discovery to “bedside” utilization in clinics.