BIOS 7302 - MIXED MODELS

[3 Credits]

Three hours of lecture per week. Rigorous course on the theory of mixed models. Essentials of relevant matrix algebra; distribution of quadratic forms; models with variance-covariance components; one-way, two-way random and mixed models with fixed effects; methods of estimation of variance components; ML, REML, ANOVA; estimation of fixed effects; testing hypotheses about fixed effects; repeated measures design methods; choices of covariance structures; generalized linear mixed models. Prerequisite: BIOS 7200.